Excellent movie. Above all else, it's a true movie. Not true like "wow, it's a true story," true like it's genuine. Every moment that has any potential for melodrama is artfully dodged in favor of something more real.
As always, Gael Garcia Bernal kicks ass. Mostly for his acting, which was excellent as always, but partly for his depiction of asthma attacks. He scared the living shit out of my shit, long after that shit had been scared out of me. I spent a solid month or two doing almost exactly what Ernesto does... unable to sleep or breathe, puke flying all over the place, certain I was within a few seconds of dying, over and over again for, ohhhh, six hours. Once a night. Scariest feeling I've ever had. I'm seizing up just thinking about what it felt like when it happened to me. So Gael, if you're reading, you got that part right.
Anyway, great movie, highly recommended.